DOTAREM 0.5 MG 20 ML

Product Overview

Dotarem 0.5 mmol/ml 20ml is a cutting-edge gadolinium-based contrast agent (GBCA) developed by Guerbet, a leader in medical imaging. Specifically formulated for use in Magnetic Resonance Imaging (MRI), this solution significantly enhances the contrast of internal body structures, crucial for accurate diagnostic imaging. It is primarily utilized by healthcare professionals to improve the visualization of brain, spine, and other tissue lesions, thereby elevating diagnostic precision. Administered intravenously, Dotarem plays a vital role in identifying pathologies that might otherwise be missed or indistinct.

Key Benefits

• Enhanced Diagnostic Accuracy: Facilitates clearer visualization of anatomical structures and pathological lesions in MRI scans, especially in the brain and spine.
• Improved Lesion Detection: Aids in the precise identification and delineation of various lesions, including tumors, inflammatory processes, and vascular abnormalities.
• Trusted Formulation: Contains gadoteric acid, a macrocyclic gadolinium chelate known for its high stability and safety profile when used appropriately.
• Professional Use: Designed for intravenous administration by trained healthcare professionals in a clinical setting, ensuring optimal safety and efficacy.

How to Use

Dotarem 0.5 mmol/ml solution for injection is strictly for intravenous administration by trained medical personnel. Dosage and timing are determined by the patient's body weight and the specific MRI procedure.

1. Preparation: Ensure aseptic conditions for preparation and administration.
2. Dosage: The standard adult dose is 0.1 mmol/kg body weight, administered as a single intravenous bolus injection.
3. Administration: Inject intravenously, typically into a peripheral vein.
4. MRI Procedure: The MRI scan should commence shortly after administration of the contrast agent, following standard imaging protocols.
5. Disposal: Dispose of any unused portion and all materials in accordance with local regulations.

Caution & Warnings

• Hypersensitivity Reactions: Patients should be monitored for signs of hypersensitivity reactions during and after administration. Emergency resuscitation equipment should be available.
• Renal Impairment: Use with caution in patients with severe renal impairment due to the risk of Nephrogenic Systemic Fibrosis (NSF). Assessment of renal function is recommended prior to administration.
• Pregnancy and Lactation: Should only be used during pregnancy if clearly necessary. Exercise caution when administered to a nursing woman.
• Extravasation: Avoid extravasation during injection, as it may cause local pain and inflammation.
• Drug Interactions: Inform your healthcare professional about all medications you are currently taking.
• Pediatric Use: Dosage for pediatric patients is determined by body weight and clinical need.

Ingredients

• Active Ingredient: Gadoteric acid (as meglumine gadoterate) 0.5 mmol/ml
• Excipients: Meglumine, Water for Injections.

Product Details

• Brand: Guerbet
• Manufacturer: Guerbet
• Form: Solution for Injection
• Strength: 0.5 mmol/ml
• Package Size: 20ml vial or pre-filled syringe
• Storage Conditions: Store below 25°C. Protect from light. Do not freeze.

For professional use only. Always consult with a qualified healthcare provider for specific medical advice and treatment.